Composition:
Amlodipine Besilate 5mg

Uses / Indication

• Management of hypertension (high blood pressure)
• Treatment of chronic stable angina and vasospastic angina (Prinzmetal’s angina)
• Reduces the risk of stroke and heart attack in hypertensive patients
• Can be used alone or in combination with other antihypertensive agents

Direction of Use

• As directed by the physician

Side Effects

• Dizziness or lightheadedness
• Headache
• Fatigue
• Flushing
• Peripheral edema (swelling of ankles or feet)
• Rare: palpitations, abdominal pain, gingival hyperplasia

Warnings / Interactions / Caution:

Warnings

• Use with caution in patients with severe aortic stenosis, heart failure, or liver impairment
• Monitor blood pressure regularly during treatment
• Not recommended in pregnancy unless absolutely necessary

Interactions

• May enhance the effects of other antihypertensives, increasing risk of hypotension
• Use caution with CYP3A4 inhibitors (e.g., ketoconazole, erythromycin) which may increase amlodipine levels
• Grapefruit juice may affect drug metabolism

Caution

• Avoid sudden discontinuation of the drug
• Inform physician of any existing medical conditions or medications being taken
• May cause dizziness; avoid driving or operating machinery until effects are known