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Composition

• Omeprazole – 20 mg per capsule
• Excipients: lactose, starch, magnesium stearate, microcrystalline cellulose, capsule shell materials

Drug class:

• Proton Pump Inhibitor (PPI)

Uses / Indications

Omezole is used for:

• Gastric and duodenal ulcers
• Gastroesophageal reflux disease (GERD)
• Erosive esophagitis
• Zollinger-Ellison syndrome (acid hypersecretion)
• Prevention of NSAID-induced gastric ulcers

Mechanism:

• Omeprazole irreversibly inhibits the H⁺/K⁺ ATPase pump in gastric parietal cells, reducing gastric acid secretion.

Direction for Use

• Adults: 20 mg once daily, usually before breakfast, or as directed by a physician
• Children: Dose adjusted by a doctor based on age/weight
• Swallow capsules whole, do not crush or chew

Side Effects

Common side effects:

• Headache
• Nausea, vomiting
• Stomach pain, diarrhea, constipation
• Flatulence

Rare but serious side effects:

• Severe allergic reaction
• Liver enzyme abnormalities
• Vitamin B12 deficiency with long-term use
• Hypomagnesemia with prolonged therapy

Warnings / Interactions / Cautions

• Take before meals for best effect
• Avoid abrupt discontinuation if on long-term therapy
• Use cautiously in patients with:
• Severe liver disease
• Osteoporosis risk (long-term use)
• Low magnesium or calcium levels
• May interact with drugs like clopidogrel, warfarin, phenytoin, diazepam, and certain antifungals
• Pregnancy and breastfeeding: use only if clearly needed