PRODUCT DETAILS

Composition

• Carvedilol 12.5mg

Uses / Indication

• Hypertension (high blood pressure)
• Congestive heart failure (CHF)
• Left ventricular dysfunction following myocardial infarction (heart attack)
• Angina (chest pain)

Direction of Use

• Taken orally, usually once or twice daily as prescribed
• Should be taken with food to slow absorption and reduce the risk of side effects like dizziness
• Dosage is typically started low and gradually increased based on tolerance and response
• Do not stop taking suddenly without consulting a doctor, especially in patients with heart conditions

Side Effects

Common:

• Dizziness, fatigue
• Low blood pressure (hypotension)
• Slow heart rate (bradycardia)
• Weight gain, fluid retention (especially in heart failure patients)
• Diarrhea or nausea

Serious:

• Worsening heart failure
• Severe bradycardia or AV block
• Bronchospasm (especially in asthmatic patients)
• Liver dysfunction
• Allergic reactions (rash, itching, swelling)

Warning / Interactions / Caution

Warnings:

• Use caution in patients with asthma or chronic obstructive pulmonary disease (COPD) due to potential for bronchospasm
• Monitor blood pressure, heart rate, and signs of heart failure regularly
• May mask symptoms of hypoglycemia in diabetic patients (e.g., rapid heartbeat)

Drug Interactions:

• Other antihypertensives and diuretics: additive blood pressure-lowering effects
• Calcium channel blockers (e.g., verapamil, diltiazem): risk of bradycardia or heart block
• Insulin and oral antidiabetics: enhanced hypoglycemic effect
• CYP2D6 inhibitors (e.g., fluoxetine, paroxetine): may increase carvedilol levels

Cautions:

• Use with caution in liver impairment; dosage adjustment may be needed
• Not recommended during pregnancy unless clearly necessary
• Breastfeeding is not advised, as it may pass into breast milk
• Elderly patients may be more sensitive to its blood pressure-lowering effects